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KMID : 0061119820100000055
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Bulletin of the Clinical Research Institute
1982 Volume.10 No. 0 p.55 ~ p.55
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The Effect of Viscoelastic Substance on corneal Endothelial Cell Loss during Penetration Keratoplasty in Cat
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Huh Warne
Rhee Sang-Wook
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Abstract
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Sodium hyaluronate (Healon) and sodium chondroitin sulfate WDS) were used during penetrating keratoplasty to determine the protective effect on corneal endothelium in cat. Four weeks postoperatively, we counted the number of corneal endothelium in control group, Healon treated group and CDS treated group using clinical specular microscope.
The results were as follows;
1. In the control group, the endothelial cell loss averaged 41% and the cell density was 1,340±60 cells/sgmm (p <.0.001).
2. In the Healon treated group, the mean endothelial cell loss averaged 23% and the cell density was 1,698±100 cells/sgmm (p <0.001).
3. In the CDS treated group, the mean endothelial cell lossaveraged 23% and the cell density was 1,701±104 cells/sgmm (p<0.001).
4. The loss of endothelial´ cells` was much smaller in the Healon-treated and CDS treated groups than in the control group (p <0A01).
5. The difference in endothelial cell loss between the Healon-treated and CDS treated groups was not statistically significant.
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KEYWORD
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